Factors Affecting Antiretroviral Therapy Adherence in Individuals with HIV in Kaimana District of Papua Barat

Chinta Novianti Mufara, Sri Yona


Objective: The present study aimed to identify factors affecting the adherence of individuals with human immunodeficiency virus-acquired immunodeficiency syndrome (HIV-AIDS) to antiretroviral therapy (ART) in Kaimana Hospital.
Methods: The study design was descriptive correlational with a cross-sectional approach. Consecutive sampling was employed to obtain 81 respondents. Data were analyzed using chi-square and multivariate logistic regression analyses.
Results: The results suggested that most respondents (74.1%) exhibited low medication adherence. The most significant factors that affect adherence were knowledge on HIV [odds ratio (OR) 10.748, p = 0.001], time since HIV diagnosis (OR 0.173, p = 0.018), alcohol consumption of 1–2 glasses/day (OR 0.184, p = 0.033), alcohol consumption of >2 glasses/day (OR 0.077, p = 0.027), and alcohol consumption of 0–1 glass/day (p = 0.040).
Conclusion: Patients with HIV-AIDS having better knowledge on HIV-AIDS and their own health condition had higher ART adherence. Moreover, patients with higher alcohol consumption with longer time since HIV diagnosis had lower medication adherence. The study result suggested improving the administration of antiretroviral regimen and increasing the knowledge of individuals with HIV-AIDS regarding their own health status as measures to improve adherence.

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